The pancreas is a 6 inch long organ located behind the stomach in the back of the abdomen. It is sponge and shaped like a fish, extended horizontally across the abdomen. The pancreas contains exocrine and endocrine glands that create pancreatic juice, hormones, and insulin.

Pancreatic cancer occurs when this uncontrolled cell growth begins in the pancreas. These abnormal cells continue dividing and form lumps pr masses of tissue called tumors. Then, tumor interferes with the main functions of the pancreas.

PANCREATIC CANCER

Pancreatic cancer occurs when cells in pancreas develop mutations in their DNA. These mutations cause cells to grow uncontrolled and to continue living after normal cells would die. Then, these accumulating cells can form a tumor. The causes include:

• The DNA type

Cells can experience uncontrolled growth if there is damage or mutations in the DNA, and therefore, damage to the genes involved in cell division. Other than that, cancer occurs when a cell gene mutation make the cell unable to correct DNA damage and unable to commit suicide. Besides, cancer is a result of mutations that inhibit oncogene and tumor suppressor gene functions, leading to uncontrolled cell growth.

• The family type

The pancreatic cancer can be the result of a genetic predisposition that is inherited from family members. This is because about 10 % of pancreatic cancers are thought to be caused by inherited gene mutations. Other than that, it is possible to be born with certain genetic mutations or a fault in a gene that make bone statistically more likely to develop cancer later in life.

• Carcinogens

If our bodies are exposed to carcinogens, free radicals are formed that try to steal electrons from other molecules in the body. Carcinogens are a class of substance that is directly responsible for damaging DNA, promoting or aiding cancer. Some of chemical used in metal refining are thought to be carcinogens, free radicals are formed that try to steal electrons from other molecules in the body.

• Traits, Habits and diet

Smoking cigarettes increases risk of pancreatic cancer. Pancreatic cancer is more likely to exist in men than in women, among Africa-American than among whites. People who do not exercise much and who are obese are more likely to develop pancreatic cancer. Alcohol consumption is also considered a risk factor for pancreatic cancer. Other than that, those who eat diets low in vegetables and fruits and high in red meat and fat are more likely to be diagnosed with the disease.

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